T2tx is a groundbreaking software platform designed to transform the management of childhood systemic lupus erythematosus (cSLE), enabling personalised disease monitoring, proactive care, and improved patient outcomes through collaboration between clinicians, patients, and families.
Transforming Challenges into Solutions: How T2Tx Could Change Chronic Disease Care

Childhood systemic lupus erythematosus (cSLE) is a rare and complex autoimmune disease that poses significant challenges for young patients, their families, and clinicians. Unlike adult lupus, cSLE often leads to more severe outcomes, including organ damage to the kidneys, brain, and heart. Managing this unpredictable condition requires a highly tailored and proactive approach, yet existing tools and systems fall short of addressing these needs.
Dr Eve Smith, PhD, MBChB, BSc, and the team at Alder Hey Innovation are tackling these challenges head-on with the development of Treat to Target (T2Tx), a groundbreaking software platform designed to revolutionise how cSLE is managed and monitored.
A Game-Changer in Chronic Disease Management
T2Tx is an innovative solution that streamlines the management of cSLE, enabling clinicians to make more informed treatment decisions while empowering patients and families to take an active role in their care. The software incorporates insights from extensive consultations with healthcare professionals, young patients, and their families to ensure an intuitive and user-friendly design.
Key Features of T2Tx Include:
- Personalised Disease Monitoring: Advanced tools track disease progression, offering tailored insights to support clinical decision-making.
- Collaborative Care: A patient-centred approach encourages active participation by patients and families, fostering better understanding and adherence to treatment plans.
- Proactive Management: Predictive analytics and streamlined workflows help clinicians anticipate complications and adjust treatments promptly.
Anticipated Benefits for Patients and Families
The impact of T2Tx could be transformative for children living with cSLE:
- Improved Outcomes: Proactive disease management may lower the risk of severe organ damage.
- Reduced Hospital Admissions: Better monitoring and intervention reduce the need for emergency care.
- Enhanced Quality of Life: Patients and families benefit from a more structured, transparent, and supportive care journey.
Paving the Way for Broader Applications
Beyond cSLE, T2Tx has the potential to serve as a model for managing other chronic conditions, offering scalable benefits to healthcare systems and patients alike.
Current Progress and Future Opportunities
The T2Tx project is currently in the design, development, and testing phases, with a focus on demonstrating its effectiveness and facilitating adoption within the NHS. Close collaboration with patients, families, and clinicians ensures that the platform evolves in line with real-world needs.
Join Us in Advancing Chronic Disease Management
Alder Hey Innovation is actively seeking collaboration with experts in chronic conditions, clinical calculators, and software as a medical device. If you’re interested in working with us to shape the future of healthcare, please reach out and quote ‘T2Tx Enquiry.’ Together, we can create lasting benefits for children and families facing the challenges of chronic disease.